Prospecting for hotspot roots

Prospecting for (Campaign) Gold

Campaigns and political parties are faced with the immensely important practical challenge of financing their efforts. Raising money is instrumental to all other aims. In recent years, this task has been complicated by the need to enlist ever greater numbers of contributors to raise ever larger sums of money. At the same time, fundraising burdens are eased a bit because contributors flock toget...

Prospecting for an HIV vaccine

Human immunodeficiency virus (HIV) sets several challenges for the development of a preventative HIV vaccine. Predictable, protective natural immunity against HIV does not occur and so unlike most other diseases for which vaccines exist, there are few guideposts from natural infection. Nonetheless, six vaccine efficacy trials have occurred. One in particular, the Thai trial called RV144, showed...

Prospecting for Precision: Promises for Personalized Medicine.

Prospecting for efficient enantioselective epoxide hydrolases

Epoxide hydrolases (EHs) from microbial sources have recently been recognized as a versatile biocatalytic tool for the synthesis of enantiomerically pure epoxides and vicinal diols. Keeping in mind the potential of these compounds in pharmaceutical, agrochemical and flavour industries, a range of epoxide substrates have been analyzed using epoxide hydrolase as the catalyst. Enzymatic catalysis ...

Molecular Diagnostic for Prospecting Polyhydroxyalkanoate-Producing Bacteria

The use of molecular diagnostic techniques for bioprospecting and microbial diversity study purposes has gained more attention thanks to their functionality, low cost and quick results. In this context, ten degenerate primers were designed for the amplification of polyhydroxyalkanoate synthase (phaC) gene, which is involved in the production of polyhydroxyalkanoate (PHA)-a biodegradable, renewa...